CSC News

May 18, 2016

Does Gender Influence Risk for Alzheimer’s Disease?

Dr. Nagiza Samatova, professor of computer science at NC State University, has been awarded $45,000 by Duke University to support her research proposal entitled “Gender Differences in the Risk for Alzheimer’s Disease in ADNI-1 MCI.”
The award will run from January 1, 2016 through December 31, 2016. 
Abstract – The project will analyze cognitive, biomarker and genetic data in 398 ADNI-1 MCI subjects to discover which crosstalks are active for each individual subject, identity active pathway crosstalks for each individual patient utilizing single nucleotide polymorphism (SNP) data, and determine which of these pathway crosstalks discriminate between genders. A novel graph-based methodology is used to identify these discriminating crosstalking pathways which will be validated by building prognostic models to predict cognitive decline compared to models using non-gender-specific biomarkers.
For more information on Dr. Samatova, click here.

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